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Intrauterine insemination (IUI) is the placing of sperm into a woman’s uterus when she is ovulating. This process is used for pair with unexplained infertility, minimal male factor infertility, and women with cervical mucus problems. IUI is often done in conjunction with ovulation-stimulating drugs. IUI can be present using the husband’s sperm or donor sperm. Before IUI, the woman should be evaluated for any hormonal imbalance, infection or any structural problems. Insemination is present at the time of ovulation, generally within 24-36 hours after the LH surge is detected, or after the “trigger” injection of HCG is administered. Ovulation is predicted by a urine test kit or blood test and ultrasound. Who is IUI suitable for? IUI is suggested only if the woman has healthy fallopian tubes, preferably confirmed laparoscopic ally, and if the man’s semen analysis is regular. It may be useful for women who have cervical mucus hostility and in some cases of unexplained infertility. What does IUI involve? The chance of sensation with IUI is improved if insemination is combined with ovulation induction using small doses of fertility drugs. These are taken by the woman, and the development of the follicles on the ovary is monitored with ultrasound. The insemination is timed to take place 36-40 hours after administration of another hormone injection which triggers ovulation. Is IUI successful? Yes, for some couples, IUI is a very helpful form of treatment provides that the man’s sperm and the woman’s tubes are healthy. The success rates for IUI are usually around 10-15% per cycle.